@article{koivuniemi_revealing_2012,
title = {Revealing structural and dynamical properties of high density lipoproteins through molecular simulations},
volume = {8},
url = {http://dx.doi.org/10.1039/C1SM06742G},
doi = {10.1039/C1SM06742G},
abstract = {The structure and function of high density lipoprotein {(HDL)} particles have intrigued the scientific community for decades because of their crucial preventive role in coronary heart disease. However, it has been a taunting task to reveal the precise molecular structure and dynamics of {HDL.} Further, because of the complex composition of {HDL}, understanding the impact of its structure and dynamics on the function of {HDL} in reverse cholesterol transport has also been a major issue. Recent progress in molecular simulation methodology and computing power has made a difference, as it has enabled essentially atomistic considerations of {HDL} particles over microsecond time scales, thereby proving substantial added value to experimental research. In this article, we discuss recent highlights concerning the structure and dynamics of {HDL} particles as revealed by atomistic and coarse-grained molecular dynamics simulations. We present examples which demonstrate how simulations and experiments can be carried out in unison, showing the added value that emerges from this interplay. We also discuss the possibilities that simulations could offer to better understand the complex phenomena associated with {HDL}, the goal being to understand its function.},
number = {5},
journal = {Soft Matter},
author = {Koivuniemi, Artturi and Vattulainen, Ilpo},
year = {2012},
pages = {1262--1267}
}
@article{huang_apolipoprotein_2011,
title = {Apolipoprotein A-I structural organization in high-density lipoproteins isolated from human plasma},
volume = {18},
issn = {1545-9993},
url = {http://dx.doi.org/10.1038/nsmb.2028},
doi = {10.1038/nsmb.2028},
number = {4},
journal = {Nat Struct Mol Biol},
author = {Huang, Rong and Silva, R A Gangani D and Jerome, W Gray and Kontush, Anatol and Chapman, M John and Curtiss, Linda K and Hodges, Timothy J and Davidson, W Sean},
month = apr,
year = {2011},
pages = {416--422},
}
@article{vuorela_role_2010,
title = {Role of lipids in spheroidal high density lipoproteins},
volume = {6},
number = {10},
journal = {{PLoS} computational biology},
author = {Vuorela, T. and Catte, A. and Niemelä, {P.S.} and Hall, A. and Hyvönen, {M.T.} and Marrink, {S.J.} and Karttunen, M. and Vattulainen, I.},
year = {2010},
pages = {e1000964},
}
@article{ollila2012interfacial,
title={Interfacial tension and surface pressure of high density lipoprotein, low density lipoprotein, and related lipid droplets},
author={Ollila, OH and Lamberg, Antti and Lehtivaara, Maria and Koivuniemi, Artturi and Vattulainen, Ilpo},
journal={Biophysical journal},
volume={103},
number={6},
pages={1236--1244},
year={2012},
publisher={Elsevier}
}
@article{hdlzeta,
title = "Nanostructured lipid carriers constituted from high-density lipoprotein components for delivery of a lipophilic cardiovascular drug ",
journal = "International Journal of Pharmaceutics ",
volume = "391",
number = "1–2",
pages = "313 - 321",
year = "2010",
note = "",
issn = "0378-5173",
doi = "http://dx.doi.org/10.1016/j.ijpharm.2010.03.011",
url = "http://www.sciencedirect.com/science/article/pii/S0378517310001857",
author = "Wen-Li Zhang and Xiao Gu and Hui Bai and Ru-Hui Yang and Chen-Dong Dong and Jian-Ping Liu",
}
@article{pupu,
title={Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit.},
author={Badim{\'o}n, Juan Jos{\'e} and Badimon, Lina and Fuster, Valent{\'\i}n},
journal={Journal of Clinical Investigation},
volume={85},
number={4},
pages={1234},
year={1990},
publisher={American Society for Clinical Investigation}
}
@Article{doi:10.1021/jp301094m,
author="Heikkil{\"a}, Elena
and Gurtovenko, Andrey A.
and Martinez-Seara, Hector
and H{\"a}kkinen, Hannu
and Vattulainen, Ilpo
and Akola, Jaakko",
title={{Atomistic Simulations of Functional Au$_{144}$(SR)$_{60}$ Gold Nanoparticles in Aqueous Environment}},
journal="The J. of Phys. Chem. C",
year="2012",
volume="116",
pages="9805--9815",
file=":/srv/http/kirjasto/library/00031.pdf:PDF"
}